By PathGene Biotech · Technically reviewed by Alex Huang
Calcium HMB Powder: 84% HMB vs 99% Total Assay
PathGene supplies calcium HMB (HMB-Ca) powder, CAS 135236-72-5, with separate specifications of ≥84% HMB and ≥99.0% total content on a dry basis. Batch PGHMB-260404 reports HMB purity 91.45%, dry-basis calcium 14.53% and dry-basis total content 99.67%. Batch COA, evaluation samples and bulk supply are available; the published MOQ is 1 kg.
Why do calcium HMB quotations show 84% and 99%?
A calcium HMB specification can report more than one analytical quantity. “HMB purity” and “total content” refer to separately named test items; a 99% total-content specification should not be rewritten as 99% HMB content. A useful supplier comparison keeps the item name, method, units and calculation basis beside every number.
PathGene's in-house COA lists HMB purity, calcium assay on a dry basis, total content on a dry basis and loss on drying as separate entries. Read each result under its own reporting basis rather than adding the percentages together or assuming one universal meaning of “purity.” This makes the quotation more useful for formulation and incoming-quality review.
HMB-Ca specification and batch COA results
Batch PGHMB-260404 was produced April 4, 2026 and tested April 5, 2026. The original report describes a white crystalline powder, 25 kg/drum packaging and a two-year shelf life.
| Reported item | COA specification | Batch result |
|---|---|---|
| HMB purity | ≥84% | 91.45% |
| Calcium assay, dry basis | 13.6–14.8% | 14.53% |
| Total content, dry basis | ≥99.0% | 99.67% |
| Loss on drying | 5.0–7.5% | 6.21% |
| Bulk density | 0.3–0.6 g/mL | Conforms |
| Heavy metals | ≤10 ppm | Conforms |
These are the results reported for this specific lot. The report also lists individual heavy-metal and microbiological tests. View the original calcium HMB COA or request the documents for the lot being offered.
Confirm the salt and hydrate form
Use the full name calcium β-hydroxy-β-methylbutyrate, together with CAS 135236-72-5, in purchase documents. The reviewed PathGene COA lists formula C10H20CaO7 and formula weight 292.34 for its hydrate form. PubChem's calcium HMB compound record represents the calcium salt with formula C10H18CaO6. This illustrates why a database formula should be read together with the supplied material's hydrate declaration and COA.
A calcium HMB quotation and an HMB free-acid quotation describe different material forms. Compare the intended form, reporting basis and usable specification before comparing powder prices. For an explanation of analytical terminology, see HPLC purity versus assay.
What should a formulation team evaluate?
For capsule, tablet or powder-blend projects, review the offered sample against the target manufacturing process. Useful checks include particle size, flow, bulk density, blend uniformity and moisture control. For a water-based format, define concentration, pH and the mixing process, then evaluate the actual sample in that system.
The calcium result is also useful when a formulation team reviews the mineral contribution of the ingredient. Calculations should use the applicable specification and a confirmed analytical basis for the selected material. The above batch table records supplier quality data; it is not a finished-product dose recommendation.
Store calcium HMB powder sealed, cool, dry and protected from light. Confirm the pack size and handling conditions for the shipment being quoted. PathGene lists 1 g, 100 g, 1 kg and 25 kg packaging options, with evaluation samples available and a bulk MOQ of 1 kg.
How to compare bulk calcium HMB offers
- Identity: calcium HMB, CAS and declared hydrate form.
- Analytical specification: HMB result, calcium, total content, methods and calculation bases.
- Quality documents: lot-matched COA and relevant test information.
- Processing needs: particle size, density, moisture and target dosage form.
- Supply terms: quantity, package sizes, destination and delivery schedule.
Using the same basis helps your team compare offers efficiently. Send required quantity, destination country, application, packaging and documentation requirements through the calcium HMB powder product page to request an evaluation sample, batch COA or bulk quotation.
Sources
- PathGene in-house COA, PGHMB-260404: specification, material form and batch results.
- NIH PubChem, calcium 3-hydroxy-3-methylbutyrate: reference identity of the calcium salt.
Frequently Asked Questions
Does 99% total content mean 99% HMB?+
No. The PathGene COA lists HMB purity and dry-basis total content separately, with specifications of ≥84% and ≥99.0%, respectively.
What does batch PGHMB-260404 report?+
The original COA reports HMB purity 91.45%, dry-basis calcium 14.53%, dry-basis total content 99.67% and loss on drying 6.21%.
Why does the hydrate form matter in an HMB-Ca inquiry?+
It identifies the supplied material and helps align formula, molecular weight and analytical basis. The reviewed PathGene COA lists C10H20CaO7 and 292.34.
Can I request samples and a bulk calcium HMB quote?+
Yes. Send quantity, destination, application, packaging and document requirements. The published MOQ is 1 kg, with 25 kg packaging among the listed options.
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